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Current Role of Fibrinogen in coagulopathy connected james van der beek to anestezitrav | Latest Anesthesia
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Istanbul Medical james van der beek Faculty, liver transplantation (emergency-elective, james van der beek live from cadaver-donor) and advanced liver surgery program that was started to train in the field of anesthesia continues. Those interested can access the necessary information here: from the Archives of the Turkish Journal of Anesthesiology and Reanimation
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Coagulopathy in trauma is severe blood loss appears as a major problem. BJA in the August issue on targeted therapy james van der beek in these patients and a review article published an editor. This article describes the process of developing post-traumatic coagulopathy role in the pathophysiological events and instead of fibrinogen are mentioned:
Severe coagulation defects due to trauma, in a large loss of blood clotting factors and platelets consumption, dilutional coagulopathy seen after crystalloid and colloid replacement is based on such reasons. In addition, activation of the fibrinolytic system or hyperfibrinolysis, hypothermia, acidosis and metabolic changes also affect the coagulation system. In major blood loss, fibrinogen, platelets and coagulation factors other than early critical value is reached. Threshold limit for fibrinogen is still a matter of debate. No recommended 100 mg / dL as well as the threshold value, data from recent clinical trials compared to 150-200 mg / dl of fibrinogen levels per-operative james van der beek and post-operative bleeding tendency increased. High fibrinogen levels varying according to the amount of blood loss, have a protective effect. In patients with multiple trauma, impaired fibrin polymerization priority for early and effective correction of fibrinogen k

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